Matrix attachment regions included in a bicistronic vector enhances and stabilizes follistatin gene expressions in both transgenic cells and transgenic mice

In the present study, follistatin (FST) gene expression vectors with either a bicistronic gene transfer cassette alone, or a bicistron gene cassette carrying a matrix attachment region (MAR) were constructed and transfected to bovine fetal fibroblasts. Evaluations of both the integration and express...

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Bibliographic Details
Main Author: Xiaoming HU,Jing GUO,Chunling BAI,Zhuying WEI,Li GAO,Tingmao HU,Shorgan BOU,Guangpeng LI
Format: Article
Language:English
Published: Higher Education Press 2016-03-01
Series:Frontiers of Agricultural Science and Engineering
Subjects:
Online Access:http://academic.hep.com.cn/fase/fileup/2095-7505/PDF/1458108419518-245632918.pdf