A cohesive look at leukemogenesis: The cohesin complex and other driving mutations in AML

Acute myeloid leukemia (AML) affects tens of thousands of patients a year, yet survival rates are as low as 25% in certain populations. This poor survival rate is partially due to the vast genetic diversity of the disease. Rarely do 2 patients with AML have the same mutational profile, which makes t...

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Bibliographic Details
Main Authors: Katelyn E. Heimbruch, Alison E. Meyer, Puja Agrawal, Aaron D. Viny, Sridhar Rao
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S147655862100004X