Activation of nuclear factor-κB in the brain after experimental subarachnoid hemorrhage and its potential role in delayed brain injury.

It has been reported that inflammation is involved in brain injury after subarachnoid hemorrhage (SAH). Nuclear factor-κB (NF-κB) is a key transcriptional regulator of inflammatory genes. Here, we used pyrrolidine dithiocarbamate(PDTC), an inhibitor of NF-κB, through intracisternal injection to stud...

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Bibliographic Details
Main Authors: Wan-Chun You, Chun-Xi Wang, Yun-Xi Pan, Xin Zhang, Xiao-Ming Zhou, Xiang-Sheng Zhang, Ji-Xin Shi, Meng-Liang Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3607578?pdf=render