The anorexigenic effect of serotonin is mediated by the generation of NADPH oxidase-dependent ROS.

The anorexigenic effect of serotonin is mediated by the generation of NADPH oxidase-dependent ROS.

Serotonin (5-HT) is a central inhibitor of food intake in mammals. Thus far, the intracellular mechanisms for the effect of serotonin on appetite regulation remain unclear. It has been recently demonstrated that reactive oxygen species (ROS) in the hypothalamus are a crucial integrative target for t...

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Bibliographic Details
Main Authors: Xin-Ling Fang, Gang Shu, Jian-Jian Yu, Li-Na Wang, Jing Yang, Qing-Jie Zeng, Xiao Cheng, Zhi-Qi Zhang, Song-Bo Wang, Ping Gao, Xiao-Tong Zhu, Qian-Yun Xi, Yong-Liang Zhang, Qing-Yan Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3541393?pdf=render

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http://europepmc.org/articles/PMC3541393?pdf=render

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