"cAMP sponge": a buffer for cyclic adenosine 3', 5'-monophosphate.
BACKGROUND:While intracellular buffers are widely used to study calcium signaling, no such tool exists for the other major second messenger, cyclic AMP (cAMP). METHODS/PRINCIPAL FINDINGS:Here we describe a genetically encoded buffer for cAMP based on the high-affinity cAMP-binding carboxy-terminus o...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-11-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2766031?pdf=render |