Synthetic Studies on Erythromycin Derivatives: Reactivity of the C12-21 Alkene
The reactivity of the C12-21 alkene of some erythromycin A derivatives was studied. This double bond was easily oxidized to the corresponding epoxide with excellent stereoselectivity. A single crystal X-ray structure showed that the epoxide moiety was on the same side as the acetonide. When an eryth...
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Format: | Article |
Language: | English |
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MDPI AG
2006-01-01
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Series: | Molecules |
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Online Access: | http://www.mdpi.com/1420-3049/11/1/121/ |