Membrane and envelope virus proteins co-expressed as lysosome associated membrane protein (LAMP) fused antigens: a potential tool to develop DNA vaccines against flaviviruses

Vaccination is the most practical and cost-effective strategy to prevent the majority of the flavivirus infection to which there is an available vaccine. However, vaccines based on attenuated virus can potentially promote collateral side effects and even rare fatal reactions. Given this scenario, th...

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Bibliographic Details
Main Authors: Rafael Dhalia, Milton Maciel Jr., Fábia S.P. Cruz, Isabelle F.T. Viana, Mariana L. Palma, Thomas August, Ernesto T.A. Marques Jr.
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2009-12-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000400005