Influenza A H5N1 clade 2.3.4 virus with a different antiviral susceptibility profile replaced clade 1 virus in humans in northern Vietnam.

Prior to 2007, highly pathogenic avian influenza (HPAI) H5N1 viruses isolated from poultry and humans in Vietnam were consistently reported to be clade 1 viruses, susceptible to oseltamivir but resistant to amantadine. Here we describe the re-emergence of human HPAI H5N1 virus infections in Vietnam...

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Main Authors: Mai T Q Le, Heiman F L Wertheim, Hien D Nguyen, Walter Taylor, Phuong V M Hoang, Cuong D Vuong, Hang L K Nguyen, Ha H Nguyen, Thai Q Nguyen, Trung V Nguyen, Trang D Van, Bich T Ngoc, Thinh N Bui, Binh G Nguyen, Liem T Nguyen, San T Luong, Phuc H Phan, Hung V Pham, Tung Nguyen, Annette Fox, Cam V Nguyen, Ha Q Do, Martin Crusat, Jeremy Farrar, Hien T Nguyen, Menno D de Jong, Peter Horby
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2556101?pdf=render