Functional Implications of Glycogen Synthase Kinase-3-Mediated Tau Phosphorylation

Tau is primarily a neuronal microtubule-associated protein that has functions related to the stabilisation of microtubules. Phosphorylation of tau is an important dynamic and regulatory element involved in the binding of tau to tubulin. Thus, highly phosphorylated tau is more likely to be present in...

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Bibliographic Details
Main Authors: Diane P. Hanger, Wendy Noble
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:International Journal of Alzheimer's Disease
Online Access:http://dx.doi.org/10.4061/2011/352805