iPS-Derived Early Oligodendrocyte Progenitor Cells from SPMS Patients Reveal Deficient In Vitro Cell Migration Stimulation

The most challenging aspect of secondary progressive multiple sclerosis (SPMS) is the lack of efficient regenerative response for remyelination, which is carried out by the endogenous population of adult oligoprogenitor cells (OPCs) after proper activation. OPCs must proliferate and migrate to the l...

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Bibliographic Details
Main Authors: Lidia Lopez-Caraballo, Jordi Martorell-Marugan, Pedro Carmona-Sáez, Elena Gonzalez-Munoz
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/8/1803