RCBTB1 Deletion Is Associated with Metastatic Outcome and Contributes to Docetaxel Resistance in Nontranslocation-Related Pleomorphic Sarcomas

RCBTB1 Deletion Is Associated with Metastatic Outcome and Contributes to Docetaxel Resistance in Nontranslocation-Related Pleomorphic Sarcomas

Half of soft-tissue sarcomas are tumors with complex genomics, which display no specific genetic alterations and respond poorly to treatment. It is therefore necessary to find new therapeutic targets for these sarcomas. Despite genetic heterogeneity across samples, oncogenesis may be driven by commo...

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Bibliographic Details
Main Authors: Olivier Mauduit, Céline Brulard, Tom Lesluyes, Vanessa Delcroix, Gaëlle Pérot, Nina Choublier, Mickael Michaud, Jessica Baud, Pauline Lagarde, Alain Aurias, Jean-Michel Coindre, Lydia Lartigue, Jean-Yves Blay, Frédéric Chibon
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Cancers
Subjects:
sarcoma with complex genomics
pleomorphic sarcoma
RCBTB1
docetaxel
cancer
Online Access:http://www.mdpi.com/2072-6694/11/1/81

Internet

http://www.mdpi.com/2072-6694/11/1/81

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