Parasite fate and involvement of infected cells in the induction of CD4+ and CD8+ T cell responses to Toxoplasma gondii.

Parasite fate and involvement of infected cells in the induction of CD4+ and CD8+ T cell responses to Toxoplasma gondii.

During infection with the intracellular parasite Toxoplasma gondii, the presentation of parasite-derived antigens to CD4+ and CD8+ T cells is essential for long-term resistance to this pathogen. Fundamental questions remain regarding the roles of phagocytosis and active invasion in the events that l...

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Bibliographic Details
Main Authors: Christopher D Dupont, David A Christian, Elizabeth M Selleck, Marion Pepper, Michael Leney-Greene, Gretchen Harms Pritchard, Anita A Koshy, Sagie Wagage, Morgan A Reuter, L David Sibley, Michael R Betts, Christopher A Hunter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3983043?pdf=render

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http://europepmc.org/articles/PMC3983043?pdf=render

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