TAGLN mediated stiffness-regulated ovarian cancer progression via RhoA/ROCK pathway

TAGLN mediated stiffness-regulated ovarian cancer progression via RhoA/ROCK pathway

Abstract Background Ovarian cancer (OC) progression is an unmet medical challenge. Since omental metastases were palpated harder than their primary counterparts during cytoreductive surgery of patients with epithelial ovarian cancer (EOC), we were inspired to investigate OC progression from the pers...

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Bibliographic Details
Main Authors: Xiao Wei, Hua Lou, Dongchen Zhou, Yijuan Jia, Huayi Li, Quanfu Huang, Jingjing Ma, Zongyuan Yang, Chaoyang Sun, Yunchong Meng, Sen Xu, Xin Yang, Xiaoting Li, Teng Ji, Zhongzhen Guo, Qinglei Gao
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Ovarian cancer
Progression
Tissue mechanics
TAGLN
RhoA/ROCK
Online Access:https://doi.org/10.1186/s13046-021-02091-6

Internet

https://doi.org/10.1186/s13046-021-02091-6

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