Estimated glomerular filtration rate is a poor predictor of the concentration of middle molecular weight uremic solutes in chronic kidney disease.

BACKGROUND: Uremic solute concentration increases as Glomerular Filtration Rate (GFR) declines. Weak associations were demonstrated between estimated GFR (eGFR) and the concentrations of several small water-soluble and protein-bound uremic solutes (MW<500 Da). Since also middle molecular weight p...

Full description

Bibliographic Details
Main Authors: Nathalie Neirynck, Sunny Eloot, Griet Glorieux, Daniela V Barreto, Fellype C Barreto, Sophie Liabeuf, Aurélie Lenglet, Horst D Lemke, Ziad A Massy, Raymond Vanholder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3432070?pdf=render