PDK1 Activity Regulates Proliferation, Invasion and Growth of Hemangiomas

PDK1 Activity Regulates Proliferation, Invasion and Growth of Hemangiomas

Background: Hemangiomas are common vascular endothelial cell tumors. Abnormally activated PI3K/Akt signaling pathway is one of the most important biological characteristics of Hemangioma. 3-phosphoinositide-dependent kinase 1(PDK1), an upstream protein of Akt, regulates the activity of Akt and its d...

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Bibliographic Details
Main Authors: Ningning Zheng, Xudong Ding, Amy Sun, Rabita Jahan
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Vascular Tumor
PDK1
Hemangioma
Akt
mTOR
Online Access:http://www.karger.com/Article/FullText/430159

Internet

http://www.karger.com/Article/FullText/430159

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