Impact of prior lamivudine use on the antiviral efficacy and development of resistance to entecavir in chronic hepatitis B patients

Impact of prior lamivudine use on the antiviral efficacy and development of resistance to entecavir in chronic hepatitis B patients

Background/AimsTo determine the efficacies of entecavir (ETV) in nucleos(t)ide analogue (NA)-naïve chronic hepatitis B (CHB) patients and in those with prior lamivudine (LAM) use who did not develop resistance.MethodsWe retrospectively enrolled 337 patients with CHB who were treated with ETV (0.5 mg...

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Bibliographic Details
Main Authors: Joo An Hwang, Kee Bum Kim, Min Jae Yang, Sun Gyo Lim, Jae Chul Hwang, Jae Youn Cheong, Sung Won Cho, Soon Sun Kim
Format: Article
Language:English
Published: Korean Association for the Study of the Liver 2015-06-01
Series:Clinical and Molecular Hepatology
Subjects:
Chronic hepatitis B
Entecavir
Lamivudine
Resistance
Online Access:http://e-cmh.org/upload/pdf/cmh-21-131.pdf

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http://e-cmh.org/upload/pdf/cmh-21-131.pdf

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