Dysregulation of Protein Phosphorylation/Dephosphorylation in Alzheimer's Disease: A Therapeutic Target

Studies during the last two decades have provided new insights into the molecular mechanism of Alzheimer's disease (AD). One of the milestone findings in AD research was the demonstration that neurofibrillary degeneration characterized by tau pathology is central to the pathogenesis of AD and o...

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Bibliographic Details
Main Authors: Cheng-Xin Gong, Fei Liu, Inge Grundke-Iqbal, Khalid Iqbal
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/JBB/2006/31825