CXCR6, a newly defined biomarker of tissue-specific stem cell asymmetric self-renewal, identifies more aggressive human melanoma cancer stem cells.

CXCR6, a newly defined biomarker of tissue-specific stem cell asymmetric self-renewal, identifies more aggressive human melanoma cancer stem cells.

A fundamental problem in cancer research is identifying the cell type that is capable of sustaining neoplastic growth and its origin from normal tissue cells. Recent investigations of a variety of tumor types have shown that phenotypically identifiable and isolable subfractions of cells possess the...

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Main Authors: Rouzbeh Taghizadeh, Minsoo Noh, Yang Hoon Huh, Emilio Ciusani, Luca Sigalotti, Michele Maio, Beatrice Arosio, Maria R Nicotra, PierGiorgio Natali, James L Sherley, Caterina A M La Porta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3008677?pdf=render

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http://europepmc.org/articles/PMC3008677?pdf=render

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