The ischemic environment drives microglia and macrophage function

The ischemic environment drives microglia and macrophage function

Cells of myeloid origin such as microglia and macrophages act at the crossroads of several inflammatory mechanisms during pathophysiology. Besides pro-inflammatory activity (M1 polarization), myeloid cells acquire protective functions (M2) and participate in the neuroprotective innate mechanisms aft...

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Bibliographic Details
Main Authors: Stefano eFumagalli, Carlo ePerego, Francesca ePischiutta, Elisa R Zanier, Maria-Grazia eDe Simoni
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Neurology
Subjects:
Macrophages
Microglia
Neuroinflammation
cell morphology
Acute brain injury
phenotypical polarization
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2015.00081/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fneur.2015.00081/full

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