S100A8/A9 and sRAGE kinetic after polytrauma; an explorative observational study

Abstract Background Following tissue injury after trauma, the activation of innate immune pathways results in systemic inflammation, organ failure and an increased risk of infections. The objective of this study was to characterize the kinetics of the S100A8/S100A9 complex, a new-recognized alarmin,...

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Bibliographic Details
Main Authors: Philippe Joly, John C. Marshall, Philippe A. Tessier, Chantal Massé, Nathalie Page, Anne Julie Frenette, François Khazoom, Soazig Le Guillan, Yves Berthiaume, Emmanuel Charbonney
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13049-017-0455-0