The Finnish New Variant of <em>Chlamydia trachomatis</em> with a Single Nucleotide Polymorphism in the 23S rRNA Target Escapes Detection by the Aptima Combo 2 Test

The Finnish New Variant of <em>Chlamydia trachomatis</em> with a Single Nucleotide Polymorphism in the 23S rRNA Target Escapes Detection by the Aptima Combo 2 Test

In 2019, more than 200 cases of <i>Chlamydia trachomatis</i> negative/equivocal by the Aptima Combo 2 assay (AC2, target: 23S rRNA) with slightly elevated relative light units (RLUs), but positive by the Aptima <i>Chlamydia trachomatis</i> assay (ACT, target: 16S rRNA) have b...

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Bibliographic Details
Main Authors: Kati Hokynar, Kaisu Rantakokko-Jalava, Antti Hakanen, Marika Havana, Laura Mannonen, Pia Jokela, Satu Kurkela, Maija Lappalainen, Magnus Unemo, Mirja Puolakkainen
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Microorganisms
Subjects:
<i>Chlamydia trachomatis</i>
mutation
nucleic acid amplification test
diagnostics
false negative
Online Access:https://www.mdpi.com/2076-2607/7/8/227

Internet

https://www.mdpi.com/2076-2607/7/8/227

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