Migration arrest of chemoresistant leukemia cells mediated by MRTF-SRF pathway

Migration arrest of chemoresistant leukemia cells mediated by MRTF-SRF pathway

Abstract Background Dormant chemotherapy-resistant leukemia cells can survive for an extended period before relapse. Nevertheless, the mechanisms underlying the development of chemoresistance in vivo remain unclear. Methods Using intravital bone imaging, we characterized the behavior of murine acute...

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Bibliographic Details
Main Authors: Maho Morimatsu, Erika Yamashita, Shigeto Seno, Takao Sudo, Junichi Kikuta, Hiroki Mizuno, Daisuke Okuzaki, Daisuke Motooka, Masaru Ishii
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Inflammation and Regeneration
Subjects:
In vivo imaging
Microscopic imaging
Leukemia
Bone marrow
Cell migration
Cell motility
Online Access:http://link.springer.com/article/10.1186/s41232-020-00127-6

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http://link.springer.com/article/10.1186/s41232-020-00127-6

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