The tyrosine phosphatase SHP-2 dephosphorylated by ALV-J via its Env efficiently promotes ALV-J replication

The tyrosine phosphatase SHP-2 dephosphorylated by ALV-J via its Env efficiently promotes ALV-J replication

Avian leukosis virus subgroup J (ALV-J) generally induces hemangioma, myeloid leukosis, and immunosuppression in chickens, causing significant poultry industry economic losses worldwide. The unusual env gene of ALV-J, with low homology to other subgroups of ALVs, is associated with its unique pathog...

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Bibliographic Details
Main Authors: Tuofan Li, Jing Xie, Xiaohui Yao, Jun Zhang, Chunping Li, Dan Ren, Luyuan Li, Quan Xie, Hongxia Shao, Aijian Qin, Jianqiang Ye
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Virulence
Subjects:
alv-j
env
shp-2
phosphorylation
knockout
replication
Online Access:http://dx.doi.org/10.1080/21505594.2021.1939952

Internet

http://dx.doi.org/10.1080/21505594.2021.1939952

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