Cytoplasmic Cyclin E Is an Independent Marker of Aggressive Tumor Biology and Breast Cancer-Specific Mortality in Women over 70 Years of Age

Cytoplasmic Cyclin E Is an Independent Marker of Aggressive Tumor Biology and Breast Cancer-Specific Mortality in Women over 70 Years of Age

Multi-cohort analysis demonstrated that cytoplasmic cyclin E expression in primary breast tumors predicts aggressive disease. However, compared to their younger counterparts, older patients have favorable tumor biology and are less likely to die of breast cancer. Biomarkers therefore require interpr...

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Bibliographic Details
Main Authors: Simon J. Johnston, Binafsha M. Syed, Ruth M. Parks, Cíntia J. Monteiro, Joseph A. Caruso, Andrew R. Green, Ian O. Ellis, Kelly K. Hunt, Cansu Karakas, Khandan Keyomarsi, Kwok-Leung Cheung
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
breast cancer
cyclin e
older patients
biomarker
tumor biology
prognosis
survival
Online Access:https://www.mdpi.com/2072-6694/12/3/712

Internet

https://www.mdpi.com/2072-6694/12/3/712

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