M1-like tumor-associated macrophages activated by exosome-transferred THBS1 promote malignant migration in oral squamous cell carcinoma

M1-like tumor-associated macrophages activated by exosome-transferred THBS1 promote malignant migration in oral squamous cell carcinoma

Abstract Background Treatment strategies targeting tumor-associated macrophages (TAMs) have been proposed in cancer areas. The functional alterations of macrophages in the microenvironment during the tumorigenesis of human epithelial cancer remain poorly understood. Here, we explored phenotypic alte...

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Bibliographic Details
Main Authors: Meng Xiao, Jianjun Zhang, Wanjun Chen, Wantao Chen
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Macrophage
Exosome
THBS1
Oral squamous cell carcinoma
Migration
Online Access:http://link.springer.com/article/10.1186/s13046-018-0815-2

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http://link.springer.com/article/10.1186/s13046-018-0815-2

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