Isocitrate dehydrogenase 1 Gene Mutation Is Associated with Prognosis in Clinical Low-Grade Gliomas.

Isocitrate dehydrogenase 1 gene mutations are found in most World Health Organization grade II and III gliomas and secondary glioblastomas. Isocitrate dehydrogenase 1 mutations are known to have prognostic value in high-grade gliomas. However, their prognostic significance in low-grade gliomas remai...

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Bibliographic Details
Main Authors: Ming-Yang Li, Yin-Yan Wang, Jin-Quan Cai, Chuan-Bao Zhang, Kuan-Yu Wang, Wen Cheng, Yan-Wei Liu, Wei Zhang, Tao Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4482584?pdf=render