A Strong Humoral Immune Response Induced by a Vaccine Formulation Containing rSm29 Adsorbed to Alum Is Associated With Protection Against Schistosoma mansoni Reinfection in Mice

A Strong Humoral Immune Response Induced by a Vaccine Formulation Containing rSm29 Adsorbed to Alum Is Associated With Protection Against Schistosoma mansoni Reinfection in Mice

The helminth Schistosoma mansoni is one of main causes of human schistosomiasis, a health and economic concern in some of the world's poorest countries. Current treatment regimens can lead to serious side effects and are not suitable for breastfeeding mothers. As such, efforts have been underta...

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Bibliographic Details
Main Authors: Clarice Carvalho Alves, Neusa Araujo, Wilma Patrícia de Oliveira Santos Bernardes, Mariana Moreira Mendes, Sergio Costa Oliveira, Cristina Toscano Fonseca
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
Sm29
alum
MPLA-SM
Schistosoma mansoni
vaccine
reinfection
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02488/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02488/full

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