Imputation-based analysis of association studies: candidate regions and quantitative traits.
We introduce a new framework for the analysis of association studies, designed to allow untyped variants to be more effectively and directly tested for association with a phenotype. The idea is to combine knowledge on patterns of correlation among SNPs (e.g., from the International HapMap project or...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-07-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC1934390?pdf=render |