Mouse embryonic palatal mesenchymal cells maintain stemness through the PTEN-Akt-mTOR autophagic pathway

Mouse embryonic palatal mesenchymal cells maintain stemness through the PTEN-Akt-mTOR autophagic pathway

Abstract Background Both genetic and environmental factors are implicated in the pathogenesis of cleft palate. However, the molecular and cellular mechanisms that regulate the development of palatal shelves, which are composed of mesenchymal cells, have not yet been fully elucidated. This study aime...

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Bibliographic Details
Main Authors: Lungang Shi, Binchen Li, Binna Zhang, Congyuan Zhen, Jianda Zhou, Shijie Tang
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Stem Cell Research & Therapy
Subjects:
Autophagy
Stemness
Mouse embryonic palatal mesenchyme cells
PTEN-Akt-mTOR signaling pathway
Online Access:http://link.springer.com/article/10.1186/s13287-019-1340-8

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http://link.springer.com/article/10.1186/s13287-019-1340-8

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