Dicer expression exhibits a tissue-specific diurnal pattern that is lost during aging and in diabetes.

Dicer expression exhibits a tissue-specific diurnal pattern that is lost during aging and in diabetes.

Dysregulation of circadian rhythmicity is identified as a key factor in disease pathogenesis. Circadian rhythmicity is controlled at both a transcriptional and post-transcriptional level suggesting the role of microRNA (miRNA) and double-stranded RNA (dsRNA) in this process. Endonuclease Dicer contr...

Full description

Bibliographic Details
Main Authors: Yuanqing Yan, Tatiana E Salazar, James M Dominguez, Dung V Nguyen, Sergio Li Calzi, Ashay D Bhatwadekar, Xiaoping Qi, Julia V Busik, Michael E Boulton, Maria B Grant
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3820540?pdf=render

Internet

http://europepmc.org/articles/PMC3820540?pdf=render

Similar Items