Continuous versus cyclic progesterone exposure differentially regulates hippocampal gene expression and functional profiles.

This study investigated the impact of chronic exposure to continuous (CoP4) versus cyclic progesterone (CyP4) alone or in combination with 17β-estradiol (E2) on gene expression profiles targeting bioenergetics, metabolism and inflammation in the adult female rat hippocampus. High-throughput qRT-PCR...

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Bibliographic Details
Main Authors: Liqin Zhao, Todd E Morgan, Zisu Mao, Sharon Lin, Enrique Cadenas, Caleb E Finch, Christian J Pike, Wendy J Mack, Roberta D Brinton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3290616?pdf=render