Levels of inflammation and oxidative stress, and a role for taurine in dystropathology of the Golden Retriever Muscular Dystrophy dog model for Duchenne Muscular Dystrophy

Levels of inflammation and oxidative stress, and a role for taurine in dystropathology of the Golden Retriever Muscular Dystrophy dog model for Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy (DMD) is a fatal skeletal muscle wasting disease presenting with excessive myofibre necrosis and increased inflammation and oxidative stress. In the mdx mouse model of DMD, homeostasis of the amino acid taurine is altered, and taurine administration drastically decreases...

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Bibliographic Details
Main Authors: Jessica R. Terrill, Marisa N. Duong, Rufus Turner, Caroline Le Guiner, Amber Boyatzis, Anthony J. Kettle, Miranda D. Grounds, Peter G. Arthur
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Redox Biology
Subjects:
Golden Retriever Muscular Dystrophy (GRMD)
Duchenne Muscular Dystrophy (DMD)
Taurine
Inflammation
Oxidative stress
Protein thiol oxidation
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231716301392

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http://www.sciencedirect.com/science/article/pii/S2213231716301392

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