The dual trigger study: Rationale and study design of a prospective double-blind randomized clinical trial comparing pregnancy rates after co-administration of low dose hCG at the time of GnRH agonist trigger or 35 h later for the prevention of OHSS

Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic complication of controlled ovarian stimulation. The use of gonadotropin releasing hormone (GnRH) agonist for the trigger of oocyte maturation is effective in the prevention of OHSS although it may result in a lower pregnancy rate. The use of...

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Bibliographic Details
Main Authors: Daniel Griffin, Claudio Benadiva, Tara Budinetz, Carolina Sueldo, Andrea DiLuigi, John Nulsen, Lawrence Engmann
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Contemporary Clinical Trials Communications
Subjects:
IVF
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865417300534