Sensory Ganglia-Specific TNF Expression Is Associated With Persistent Nociception After Resolution of Inflammation

Sensory Ganglia-Specific TNF Expression Is Associated With Persistent Nociception After Resolution of Inflammation

Joint pain is a distressing symptom of arthritis, and it is frequently persistent even after treatments which reduce local inflammation. Continuous production of algogenic factors activate/sensitize nociceptors in the joint structures and contribute to persistent pain, a challenging and difficult co...

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Bibliographic Details
Main Authors: William Antonio Gonçalves, Barbara Maximino Rezende, Marcos Paulo Esteves de Oliveira, Lucas Secchim Ribeiro, Victor Fattori, Walison Nunes da Silva, Pedro Henrique Dias Moura Prazeres, Celso Martins Queiroz-Junior, Karina Talita de Oliveira Santana, Walyson Coelho Costa, Vinícius Amorim Beltrami, Vivian Vasconcelos Costa, Alexander Birbrair, Waldiceu A. Verri, Fernando Lopes, Thiago Mattar Cunha, Mauro Martins Teixeira, Flávio Almeida Amaral, Vanessa Pinho
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
resolution of inflammation
arthritis
pain
TNF
neuroinflammation
dorsal root ganglia
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.03120/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.03120/full

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