“Hemophagocytic Lymphohistiocytosis after EBV reactivation and ibrutinib treatment in relapsed/refractory Chronic Lymphocytic Leukemia”

“Hemophagocytic Lymphohistiocytosis after EBV reactivation and ibrutinib treatment in relapsed/refractory Chronic Lymphocytic Leukemia”

Hemophagocytic Lymphohistiocytosis (HLH) is a rare syndrome characterized by ineffective T-cell and NK response. We report the clinical course of a patient with relapsed CLL who developed acute symptoms soon after starting ibrutinib. Hyperpyrexia, splenomegaly, hyperferritinemia, hypertriglyceridemi...

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Bibliographic Details
Main Authors: Maurizio Cavallari, Maria Ciccone, Simonetta Falzoni, Francesco Cavazzini, Luca Formigaro, Francesco Di Virgilio, Antonella Rotola, Gian Matteo Rigolin, Antonio Cuneo
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Leukemia Research Reports
Subjects:
Hemophagocytic Lymphohisticytosis
Chronic Lymphocytic Leukemia
Epstein-barr virus
Ibrutinib
Anti-cytokine therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2213048916300437

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http://www.sciencedirect.com/science/article/pii/S2213048916300437

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