Plasminogen Activator Inhibitor 1 for Predicting Sepsis Severity and Mortality Outcomes: A Systematic Review and Meta-Analysis

Plasminogen Activator Inhibitor 1 for Predicting Sepsis Severity and Mortality Outcomes: A Systematic Review and Meta-Analysis

ObjectivesPlasminogen activator inhibitor-1 (PAI-1), a crucial regulator of fibrinolysis, is increased in sepsis, but its values in predicting disease severity or mortality outcomes have been controversial. Therefore, we conducted a systematic review and meta-analysis of its predictive values in sep...

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Bibliographic Details
Main Authors: Timothy L. Tipoe, William K. K. Wu, Lilianna Chung, Mengqi Gong, Mei Dong, Tong Liu, Leonardo Roever, Jeffery Ho, Martin C. S. Wong, Matthew T. V. Chan, Gary Tse, Justin C. Y. Wu, Sunny H. Wong
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
plasminogen activator inhibitor-1
sepsis
mortality
meta-analysis
systematic review
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01218/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01218/full

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