Drug Resistance Modulation in Staphylococcus Aureus, a New Biological Activity for Mesoionic Hydrochloride Compounds

Drug Resistance Modulation in Staphylococcus Aureus, a New Biological Activity for Mesoionic Hydrochloride Compounds

Two salts of the mesoionic compounds 1,4-diphenyl-5-(5-nitro-2-furanyl)-1,3,4-thiadiazolium-2-thiol chloride (MC-1) and 4-phenyl-5-(5-nitro-2-furanyl)-1,3,4-thiadiazolium-2-phenylamine chloride (MC-2) were synthesized utilizing 1,4-diphenyl-thiosemicarbazide and 5-nitro-2-furoyl chloride as starting...

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Bibliographic Details
Main Authors: Petrônio Filgueiras de Athayde-Filho, Cledualdo Soares de Oliveira, David Peter Harding, Bruno Freitas Lira, Jorge Gonçalo Fernandes Lorenzo, José Pinto Siqueira-Júnior, José Maria Barbosa-Filho, Vivyanne dos Santos Falcão-Silva
Format: Article
Language:English
Published: MDPI AG 2011-02-01
Series:Molecules
Subjects:
mesoionic compounds
modulation of drug resistance
efflux pump inhibitor
Online Access:http://www.mdpi.com/1420-3049/16/3/2023/

Internet

http://www.mdpi.com/1420-3049/16/3/2023/

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