Development of a one-step probe based molecular assay for rapid immunodiagnosis of infection with M. tuberculosis using dried blood spots.

Development of a one-step probe based molecular assay for rapid immunodiagnosis of infection with M. tuberculosis using dried blood spots.

BACKGROUND:Antigen specific release of IP-10 is the most promising alternative marker to IFN-γ for infection with M. tuberculosis. Compared to Interferon-γ release assays (IGRA), IP-10 is released in high levels enabling novel approaches such as field friendly dried blood spots (DBS) and molecular d...

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Bibliographic Details
Main Authors: Thomas Blauenfeldt, Jan Heyckendorf, Sidse Graff Jensen, Christoph Lange, Camilla Drabe, Thomas S Hermansen, Lena de Thurah, Troels Lillebaek, Jesper Eugen-Olsen, Niels Seersholm, Søren Hoff, Jesper Bonde, Morten Ruhwald
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4153573?pdf=render

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http://europepmc.org/articles/PMC4153573?pdf=render

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