NK Cells Augment Oncolytic Adenovirus Cytotoxicity in Ovarian Cancer

NK Cells Augment Oncolytic Adenovirus Cytotoxicity in Ovarian Cancer

Oncolytic viruses (OVs) can trigger profound innate and adaptive immune responses, which have the potential both to potentiate and reduce the activity of OVs. Natural killer (NK) cells can mediate potent anti-viral and anti-tumoral responses, but there are no data on the role of NK cells in oncolyti...

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Bibliographic Details
Main Authors: Elaine Y.L. Leung, Darren P. Ennis, Philippa R. Kennedy, Christopher Hansell, Suzanne Dowson, Malcolm Farquharson, Pavlina Spiliopoulou, Jaya Nautiyal, Sophie McNamara, Leo M. Carlin, Kerry Fisher, Daniel M. Davis, Gerard Graham, Iain A. McNeish
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770520300218

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http://www.sciencedirect.com/science/article/pii/S2372770520300218

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