Evolution of HIV-1 within untreated individuals and at the population scale in Uganda.

HIV-1 undergoes multiple rounds of error-prone replication between transmission events, resulting in diverse viral populations within and among individuals. In addition, the virus experiences different selective pressures at multiple levels: during the course of infection, at transmission, and among...

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Bibliographic Details
Main Authors: Jayna Raghwani, Andrew D Redd, Andrew F Longosz, Chieh-Hsi Wu, David Serwadda, Craig Martens, Joseph Kagaayi, Nelson Sewankambo, Stephen F Porcella, Mary K Grabowski, Thomas C Quinn, Michael A Eller, Leigh Anne Eller, Fred Wabwire-Mangen, Merlin L Robb, Christophe Fraser, Katrina A Lythgoe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007167