The -144C/A polymorphism in the promoter of HSP90beta is associated with multiple organ dysfunction scores.

INTRODUCTION: Variations in genetic background are the leading cause of differential susceptibility to traumatic infection. Heat shock protein 90 (HSP90), a broadly distributed and conserved molecule, regulates inflammation under stressful and traumatic conditions. However, the relationships between...

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Bibliographic Details
Main Authors: Yan Zhao, Liju Tao, Dongpo Jiang, Xingyun Chen, Ping Li, Yalei Ning, Renping Xiong, Ping Liu, Yizhi Peng, Yuan-Guo Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3596273?pdf=render