Peptides of major basic protein and eosinophil cationic protein activate human mast cells

The eosinophil granule proteins, major basic protein (MBP) and eosinophil cationic protein (ECP), activate mast cells during inflammation; however the mechanism responsible for this activity is poorly understood. We found that some theoretical tryptase-digested fragments of MBP and ECP induced degra...

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Bibliographic Details
Main Authors: Hiroyuki Ogasawara, Masahiro Furuno, Koji Edamura, Masato Noguchi
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Biochemistry and Biophysics Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580819302298