Reduced susceptibility to praziquantel among naturally occurring Kenyan isolates of Schistosoma mansoni.

The near exclusive use of praziquantel (PZQ) for treatment of human schistosomiasis has raised concerns about the possible emergence of drug-resistant schistosomes.We measured susceptibility to PZQ of isolates of Schistosoma mansoni obtained from patients from Kisumu, Kenya continuously exposed to i...

Full description

Bibliographic Details
Main Authors: Sandra D Melman, Michelle L Steinauer, Charles Cunningham, Laura S Kubatko, Ibrahim N Mwangi, Nirvana Barker Wynn, Martin W Mutuku, Diana M S Karanja, Daniel G Colley, Carla L Black, William Evan Secor, Gerald M Mkoji, Eric S Loker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2721635?pdf=render