XRCC2 Regulates Replication Fork Progression during dNTP Alterations

Summary: RAD51 paralogs are essential for maintenance of genomic integrity through protection of stalled replication forks and homology-directed repair (HDR) of double-strand breaks. Here, we find that a subset of RAD51 paralogs, XRCC2 (FANCU) and its binding partner RAD51D, restrain active DNA synt...

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Bibliographic Details
Main Authors: Sneha Saxena, Kumar Somyajit, Ganesh Nagaraju
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471831876X