XRCC2 Regulates Replication Fork Progression during dNTP Alterations
Summary: RAD51 paralogs are essential for maintenance of genomic integrity through protection of stalled replication forks and homology-directed repair (HDR) of double-strand breaks. Here, we find that a subset of RAD51 paralogs, XRCC2 (FANCU) and its binding partner RAD51D, restrain active DNA synt...
Main Authors: | Sneha Saxena, Kumar Somyajit, Ganesh Nagaraju |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2018-12-01
|
Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221112471831876X |
Similar Items
-
Organization of the T4 dNTP synthetase complex at DNA replication sites
by: Kim, JuHyun
Published: (2012) -
Increased and imbalanced dNTP pools symmetrically promote both leading and lagging strand replication infidelity.
by: Robert J Buckland, et al.
Published: (2014-12-01) -
Regulation of ribonucleotide reductase and the role of dNTP pools in genomic stability in yeast Saccharomyces cerevisiae
by: Tsaponina, Olga
Published: (2011) -
dNTP Supply Gene Expression Patterns after P53 Loss
by: Mark Jackson, et al.
Published: (2012-11-01) -
Effect of induced dNTP pool imbalance on HIV-1 reverse transcription in macrophages
by: Caitlin Shepard, et al.
Published: (2019-10-01)