Extracellular vesicles from Leishmania-infected macrophages confer an anti-infection cytokine-production profile to naïve macrophages.

BACKGROUND:Extracellular vesicles (EVs) are structures with phospholipid bilayer membranes and 100-1000 nm diameters. These vesicles are released from cells upon activation of surface receptors and/or apoptosis. The production of EVs by dendritic cells, mast cells, macrophages, and B and T lymphocyt...

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Main Authors: André Cronemberger-Andrade, Luciana Aragão-França, Cintia Figueiredo de Araujo, Viviane Junqueira Rocha, Mariana da Cruz Borges-Silva, Cláudio P Figueira, Pablo R Oliveira, Luiz A R de Freitas, Patrícia S T Veras, Lain Pontes-de-Carvalho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4169249?pdf=render