Astrocytes influence medulloblastoma phenotypes and CD133 surface expression.

The medulloblastoma (MB) microenvironment is diverse, and cell-cell interactions within this milieu is of prime importance. Astrocytes, a major component of the microenvironment, have been shown to impact primary tumor cell phenotypes and metastasis. Based on proximity of MB cells and astrocytes in...

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Bibliographic Details
Main Authors: Emily Gronseth, Ankan Gupta, Chris Koceja, Suresh Kumar, Raman G Kutty, Kevin Rarick, Ling Wang, Ramani Ramchandran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0235852