Epstein-Barr virus LMP2A signaling <it>in statu nascendi </it>mimics a B cell antigen receptor-like activation signal

Epstein-Barr virus LMP2A signaling <it>in statu nascendi </it>mimics a B cell antigen receptor-like activation signal

<p>Abstract</p> <p>Background</p> <p>The latent membrane protein (LMP) 2A of Epstein-Barr virus (EBV) is expressed during different latency stages of EBV-infected B cells in which it triggers activation of cytoplasmic protein tyrosine kinases. Early studies revealed tha...

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Bibliographic Details
Main Authors: Engels Niklas, Yigit Gökhan, Emmerich Christoph H, Czesnik Dirk, Schild Detlev, Wienands Jürgen
Format: Article
Language:English
Published: BMC 2012-04-01
Series:Cell Communication and Signaling
Subjects:
B Cells
Epstein-Barr virus
LMP2A
B cell antigen receptor
ITAM
tyrosine phosphorylation
Ca<sup>2+</sup>
latency
lytic replication
Online Access:http://www.biosignaling.com/content/10/1/9

Internet

http://www.biosignaling.com/content/10/1/9

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