Soluble Fms-Like Tyrosine Kinase-1 Alters Cellular Metabolism and Mitochondrial Bioenergetics in Preeclampsia

Soluble Fms-Like Tyrosine Kinase-1 Alters Cellular Metabolism and Mitochondrial Bioenergetics in Preeclampsia

Preeclampsia is a maternal hypertensive disorder that affects up to 1 out of 12 pregnancies worldwide. It is characterized by proteinuria, endothelial dysfunction, and elevated levels of the soluble form of the vascular endothelial growth factor receptor-1 (VEGFR-1, known as sFlt-1). sFlt-1 effects...

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Bibliographic Details
Main Authors: Lissette C. Sánchez-Aranguren, Cindy T. Espinosa-González, Laura M. González-Ortiz, Sandra M. Sanabria-Barrera, Carlos E. Riaño-Medina, Andrés F. Nuñez, Asif Ahmed, Jeannette Vasquez-Vivar, Marcos López
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Physiology
Subjects:
preeclampsia
sFlt-1
mitochondrial dysfunction
endothelial dysfunction
oxidative stress and metabolic perturbations
metabolism
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2018.00083/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2018.00083/full

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