In vitro reconstitution of SARS-coronavirus mRNA cap methylation.

SARS-coronavirus (SARS-CoV) genome expression depends on the synthesis of a set of mRNAs, which presumably are capped at their 5' end and direct the synthesis of all viral proteins in the infected cell. Sixteen viral non-structural proteins (nsp1 to nsp16) constitute an unusually large replicas...

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Bibliographic Details
Main Authors: Mickaël Bouvet, Claire Debarnot, Isabelle Imbert, Barbara Selisko, Eric J Snijder, Bruno Canard, Etienne Decroly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20421945/pdf/?tool=EBI